EHPnet: International Maritime Organization

EHPnet: International Maritime Organization

1Department of Medical Oncology, Bristol Haematology and Oncology Centre, Horfield Road, Bristol BS2 8ED, UK 2Department of Cellular & Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK 3Richard Bright Kidney Unit, Southmead Hospital, Westbury-on-Trym, Bristol BS10 5NB, UK 4Department of Radiology, Bristol Royal Infirmary, Marlborough Street, Bristol BS2 ...

EHPnet.

After attending the sarcoma session of the 1990 meeting of the American Society for Clinical Oncology, one might be forgiven for wondering if chemotherapy for metastatic soft tissue sarcoma (STS) has come a full circle. It is 18 years since the South West Oncology Group (SWOG) published results of the first large scale study of doxorubicin (ADR) (O'Bryan et al., 1973). In 45 evaluable patients ...

EHPnet: www.fueleconomy.gov

Background: Myostatin, a muscle-specific member of the Transforming Growth Factor beta family, negatively regulates muscle development. Double-muscled (DM) cattle have a loss-offunction mutation in their myostatin gene responsible for the hypermuscular phenotype. Thus, these animals are a good model for understanding the mechanisms underpinning muscular hypertrophy. In order to identify individ...

EHPnet: Bioremediation

Background: 18F-FLT is a novel PET radiotracer which has demonstrated a strong potential utility for imaging cellular proliferation in human tumors in vivo. To facilitate future regulatory approval of 18F-FLT for clinical use, we wished to demonstrate the safety of radiotracer doses of 18F-FLT administered to human subjects, by: 1) performing an evaluation of the toxicity of 18F-FLT administere...

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